pharm math
   
Titration: Flow Rate
 
spacer iv Calculating Flow Rate (ml /hr):

Key elements:

  • Dosage must be given.
    • This may be expressed as "amount"/kg/min, units/hr, mg/min, etc.
  • Time is constant (60 min/hr).
  • Weight of the client is expressed in kilograms.
  • Concentration of the infusion.
    • When using a dosage of mcg/kg/min, the end concentration must be expressed in mcg/cc.  (Convert mg to mcg.).
    • You will need to use R & P to find how many units of a medication in a ml. (See below.)
    • Rule is: To calculate, one must have like amounts in dose and concentration.
Formula to calculate flow rate:
     
    Dose ("unit"/kg/min)  X wt in kg X 60 (min/hr)
    concentration of infusion ("unit" / ml)
Example:
For the client whose weight is 130 lbs and has dopamine ordered at 8 mcg/kg/min, what rate should the infusion pump be set for a solution of 400 mg dopamine in 250 ml D5W?
Critical information:
  • Client's weight: 130 lbs
  • Dosage: 8 mcg/kg/min
  • Solution: 400 (mg) in 250 (ml)
Tip:
1)  Convert wt to kg.  130 / 2.2 = 59.09 kg
2)  Find concentration of dopamine in 1 cc. 

 
400 mg
250 ml
= x mg
1 ml
250x = 400
x
= 1.6
3) Concentration is 1.6 mg /cc.  Convert the mg to micrograms.
1.6 (mg) x 1000 (mcg per 1 mg) = 1600 mcg/cc.

 

Now that you have gathered all the information, plug it into the formula:

 
8 ("unit"/kg/min)  X 59.09 (wt in kg) X 60 (min/hr)
1600 ("unit" / ml)
= 28363.32
1600
x
= 17.727
17.727 or 18 ( ml/hr) will dialed on the pump.
 
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01/2005
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